Using V1.0.1, since updating Joomla from 2.5.1 to 2.5.2 most times on browsing to the site with a desktop I get the following error (but not always) 

Internal Server Error
The server encountered an internal error or misconfiguration and was unable to complete your request.
Please contact the server administrator, webmaster@xxxxxx and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.

If I disable mobilejoomla plugin, the problem goes away.
Any ideas please

Please, post error message from error_log file.

HI I have a similar problem. Its working on my PC browser and on Iphone but I get internal server error 500 on android.
Testet on sevral android phones non is working. Also tried to reinstall and install on other joomla 2.5.4 sites.
Info:
Databaseversjon 5.0.67-log
Databasekollasjon utf8_general_ci
PHP-versjon 5.2.12
Nettstedstjener Apache/1.3.37
Nettstedstjener til PHP-grensesnitt cgi-fcgi
Joomla!-versjon Joomla! 2.5.4 Stable [ Ember ] 2-April-2012 14:00 GMT
Joomla-plattformversjon Joomla Platform 11.4.0 Stable [ Brian Kernighan ] 03-Jan-2012 00:00 GMT
I am using MJ v 1.0.2. I don have any error report

Do you have an idea where to start looking?

I am have exactly the same problem on two different sites. Works on all phones and desktop but 500 error code on android. Have you found a solution??

No. I hope the mobilejoomla team will help. I will post here as soon as the problem is solved with the solution

It's impossible to find a solution without error description from error_log.

Here is the error_log from one site...

[Thu Apr 19 16:08:08 2012] [error] [client 174.254.160.12] FastCGI: comm with server "/hsphere/shared/php5/bin/php" aborted: error parsing headers: duplicate header 'Content-Type'
[Thu Apr 19 16:08:15 2012] [error] [client 174.254.160.12] FastCGI: comm with server "/hsphere/shared/php5/bin/php" aborted: error parsing headers: duplicate header 'Content-Type'
[Thu Apr 19 16:09:42 2012] [error] [client 174.254.160.12] FastCGI: comm with server "/hsphere/shared/php5/bin/php" aborted: error parsing headers: duplicate header 'Content-Type'
[Thu Apr 19 16:09:42 2012] [error] [client 174.254.160.12] File does not exist: /hsphere/local/home/erievovo20/erievolvo.com/default_html, referer: www.erievolvo.com/
[Thu Apr 19 16:12:10 2012] [error] [client 174.254.160.12] FastCGI: comm with server "/hsphere/shared/php5/bin/php" aborted: error parsing headers: duplicate header 'Content-Type'
[Thu Apr 19 16:12:10 2012] [error] [client 174.254.160.12] File does not exist: /hsphere/local/home/erievovo20/erievolvo.com/default_html, referer: www.erievolvo.com/

This patch should fix issue with duplicate header 'Content-Type':
github.com/mobilejoomla/mobilejoomla/commit/8172295630f355c6295c297576c76eb299654e98

Worked like a charm!! 

Thank you!